Abstract

We introduce a robust control method of terahertz (THz) transmission by tuning filling factors of Au nanoparticles (AuNPs) inside nano slot antennas. AuNPs in sub-100 nm diameters were spread over the nano slot antennas, followed by sweeping them into the slots. AuNPs can be efficiently localized and inserted into nano slots where the THz fields are greatly enhanced, by a “squeegee” made of the polydimethylsiloxane (PDMS). The sweeping of the AuNPs results in further dramatic reduction of THz transmission by suppressing the fundamental resonance mode of the nano slot, as compared to a typical random dropping case. It definitely works for an accurate THz transmission control, as well as the removal of unwanted ions that occasionally confuse signal accuracy from the target signals. Our approach provides a complete reinterpretation of sample deposition for further steady demands in developing ultrasensitive terahertz (THz) molecule sensors.

© 2017 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Full Article  |  PDF Article
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  1. A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
    [PubMed]
  2. J. Xu, K. W. Plaxco, and S. J. Allen, “Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy,” Protein Sci. 15(5), 1175–1181 (2006).
    [PubMed]
  3. E. P. J. Parrott, Y. Sun, and E. Pickwell-MacPherson, “Terahertz spectroscopy: Its future role in medical diagnoses,” J. Mol. Struct. 1006, 66–76 (2011).
  4. P. L. Stiles, J. A. Dieringer, N. C. Shah, and R. P. Van Duyne, “Surface-Enhanced Raman spectroscopy,” Annu. Rev. Anal. Chem. (Palo Alto, Calif.) 1, 601–626 (2008).
    [PubMed]
  5. K. Ballschmiter and M. Zell, “Analysis of polychlorinated biphenyls (PCB) by glass capillary gas chromatography,” Fresenius J. Anal. Chem. 302, 20–31 (1980).
  6. L. Bokobza, “Near Infrared Spectroscopy,” J. Near Infrared Spectrosc. 6, 3–17 (1998).
  7. F. F. Jöbsis, “Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters,” Science 198(4323), 1264–1267 (1977).
    [PubMed]
  8. B. M. Fischer, M. Walther, and P. Uhd Jepsen, “Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy,” Phys. Med. Biol. 47(21), 3807–3814 (2002).
    [PubMed]
  9. M. D. King, W. Ouellette, and T. M. Korter, “Noncovalent Interactions in Paired DNA Nucleobases Investigated by Terahertz Spectroscopy and Solid-State Density Functional Theory,” J. Phys. Chem. A 115(34), 9467–9478 (2011).
    [PubMed]
  10. K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
    [PubMed]
  11. H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
    [PubMed]
  12. S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
    [PubMed]
  13. X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).
  14. S. J. Park, B. H. Son, S. J. Choi, H. S. Kim, and Y. H. Ahn, “Sensitive detection of yeast using terahertz slot antennas,” Opt. Express 22(25), 30467–30472 (2014).
    [PubMed]
  15. D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
    [PubMed]
  16. D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).
  17. D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
    [PubMed]
  18. H. Hu and R. G. Larson, “Marangoni effect reverses coffee-ring depositions,” J. Phys. Chem. B 110(14), 7090–7094 (2006).
    [PubMed]
  19. T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
    [PubMed]
  20. M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).
  21. H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).
  22. B. G. Healey and D. R. Walt, “Improved fiber-optic chemical sensor for penicillin,” Anal. Chem. 67(24), 4471–4476 (1995).
    [PubMed]
  23. H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
    [PubMed]
  24. L. B. Sheiner and S. L. Beal, “Evaluation of methods for estimating population pharmacokinetic parameters. II. Biexponential model and experimental pharmacokinetic data,” J. Pharmacokinet. Biopharm. 9(5), 635–651 (1981).
    [PubMed]

2017 (1)

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

2016 (2)

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

2015 (1)

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

2014 (2)

S. J. Park, B. H. Son, S. J. Choi, H. S. Kim, and Y. H. Ahn, “Sensitive detection of yeast using terahertz slot antennas,” Opt. Express 22(25), 30467–30472 (2014).
[PubMed]

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

2013 (1)

H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
[PubMed]

2011 (2)

E. P. J. Parrott, Y. Sun, and E. Pickwell-MacPherson, “Terahertz spectroscopy: Its future role in medical diagnoses,” J. Mol. Struct. 1006, 66–76 (2011).

M. D. King, W. Ouellette, and T. M. Korter, “Noncovalent Interactions in Paired DNA Nucleobases Investigated by Terahertz Spectroscopy and Solid-State Density Functional Theory,” J. Phys. Chem. A 115(34), 9467–9478 (2011).
[PubMed]

2010 (1)

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

2009 (1)

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

2008 (2)

H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
[PubMed]

P. L. Stiles, J. A. Dieringer, N. C. Shah, and R. P. Van Duyne, “Surface-Enhanced Raman spectroscopy,” Annu. Rev. Anal. Chem. (Palo Alto, Calif.) 1, 601–626 (2008).
[PubMed]

2006 (3)

J. Xu, K. W. Plaxco, and S. J. Allen, “Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy,” Protein Sci. 15(5), 1175–1181 (2006).
[PubMed]

H. Hu and R. G. Larson, “Marangoni effect reverses coffee-ring depositions,” J. Phys. Chem. B 110(14), 7090–7094 (2006).
[PubMed]

T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
[PubMed]

2005 (1)

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

2002 (2)

A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
[PubMed]

B. M. Fischer, M. Walther, and P. Uhd Jepsen, “Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy,” Phys. Med. Biol. 47(21), 3807–3814 (2002).
[PubMed]

1998 (1)

1995 (1)

B. G. Healey and D. R. Walt, “Improved fiber-optic chemical sensor for penicillin,” Anal. Chem. 67(24), 4471–4476 (1995).
[PubMed]

1981 (1)

L. B. Sheiner and S. L. Beal, “Evaluation of methods for estimating population pharmacokinetic parameters. II. Biexponential model and experimental pharmacokinetic data,” J. Pharmacokinet. Biopharm. 9(5), 635–651 (1981).
[PubMed]

1980 (1)

K. Ballschmiter and M. Zell, “Analysis of polychlorinated biphenyls (PCB) by glass capillary gas chromatography,” Fresenius J. Anal. Chem. 302, 20–31 (1980).

1977 (1)

F. F. Jöbsis, “Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters,” Science 198(4323), 1264–1267 (1977).
[PubMed]

Ahn, K. J.

H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
[PubMed]

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

Ahn, Y. H.

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

S. J. Park, B. H. Son, S. J. Choi, H. S. Kim, and Y. H. Ahn, “Sensitive detection of yeast using terahertz slot antennas,” Opt. Express 22(25), 30467–30472 (2014).
[PubMed]

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

Allen, S. J.

J. Xu, K. W. Plaxco, and S. J. Allen, “Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy,” Protein Sci. 15(5), 1175–1181 (2006).
[PubMed]

Bahk, Y.-M.

H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
[PubMed]

Ballschmiter, K.

K. Ballschmiter and M. Zell, “Analysis of polychlorinated biphenyls (PCB) by glass capillary gas chromatography,” Fresenius J. Anal. Chem. 302, 20–31 (1980).

Beal, S. L.

L. B. Sheiner and S. L. Beal, “Evaluation of methods for estimating population pharmacokinetic parameters. II. Biexponential model and experimental pharmacokinetic data,” J. Pharmacokinet. Biopharm. 9(5), 635–651 (1981).
[PubMed]

Berry, E.

A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
[PubMed]

Bigioni, T. P.

T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
[PubMed]

Bokobza, L.

Chamberlain, J. M.

A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
[PubMed]

Chen, Q.

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Choi, S. J.

S. J. Park, B. H. Son, S. J. Choi, H. S. Kim, and Y. H. Ahn, “Sensitive detection of yeast using terahertz slot antennas,” Opt. Express 22(25), 30467–30472 (2014).
[PubMed]

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

Choi, S. S.

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Corwin, E. I.

T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
[PubMed]

Cumming, D. R. S.

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Dieringer, J. A.

P. L. Stiles, J. A. Dieringer, N. C. Shah, and R. P. Van Duyne, “Surface-Enhanced Raman spectroscopy,” Annu. Rev. Anal. Chem. (Palo Alto, Calif.) 1, 601–626 (2008).
[PubMed]

Fischer, B. M.

B. M. Fischer, M. Walther, and P. Uhd Jepsen, “Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy,” Phys. Med. Biol. 47(21), 3807–3814 (2002).
[PubMed]

Fitzgerald, A. J.

A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
[PubMed]

Han, S.

H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
[PubMed]

Han, S. T.

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

Hanson, M. A.

H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
[PubMed]

Healey, B. G.

B. G. Healey and D. R. Walt, “Improved fiber-optic chemical sensor for penicillin,” Anal. Chem. 67(24), 4471–4476 (1995).
[PubMed]

Hong, J. T.

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

Hu, H.

H. Hu and R. G. Larson, “Marangoni effect reverses coffee-ring depositions,” J. Phys. Chem. B 110(14), 7090–7094 (2006).
[PubMed]

Hu, X.

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Jaeger, H. M.

T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
[PubMed]

Jhon, Y. M.

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

Jöbsis, F. F.

F. F. Jöbsis, “Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters,” Science 198(4323), 1264–1267 (1977).
[PubMed]

Kang, J. H.

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Kang, J.-H.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Kim, C.

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Kim, D. S.

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Kim, D.-S.

H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
[PubMed]

Kim, G.

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

Kim, H. S.

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

S. J. Park, B. H. Son, S. J. Choi, H. S. Kim, and Y. H. Ahn, “Sensitive detection of yeast using terahertz slot antennas,” Opt. Express 22(25), 30467–30472 (2014).
[PubMed]

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

Kim, H.-S.

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Kim, J. H.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

King, M. D.

M. D. King, W. Ouellette, and T. M. Korter, “Noncovalent Interactions in Paired DNA Nucleobases Investigated by Terahertz Spectroscopy and Solid-State Density Functional Theory,” J. Phys. Chem. A 115(34), 9467–9478 (2011).
[PubMed]

Koo, S. M.

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Korter, T. M.

M. D. King, W. Ouellette, and T. M. Korter, “Noncovalent Interactions in Paired DNA Nucleobases Investigated by Terahertz Spectroscopy and Solid-State Density Functional Theory,” J. Phys. Chem. A 115(34), 9467–9478 (2011).
[PubMed]

Kostov, Y.

H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
[PubMed]

Kwon, J.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

Kyoung, J. S.

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

Lakowicz, J. R.

H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
[PubMed]

Larson, R. G.

H. Hu and R. G. Larson, “Marangoni effect reverses coffee-ring depositions,” J. Phys. Chem. B 110(14), 7090–7094 (2006).
[PubMed]

Lee, D.-K.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Lee, J.-S.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Lee, S.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

Lee, T.

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Lin, X.-M.

T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
[PubMed]

Murakami, H.

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

Nguyen, T. T.

T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
[PubMed]

Ohtake, H.

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

Ouellette, W.

M. D. King, W. Ouellette, and T. M. Korter, “Noncovalent Interactions in Paired DNA Nucleobases Investigated by Terahertz Spectroscopy and Solid-State Density Functional Theory,” J. Phys. Chem. A 115(34), 9467–9478 (2011).
[PubMed]

Park, D. J.

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Park, G. S.

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Park, H. R.

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Park, H.-R.

H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
[PubMed]

Park, J. Y.

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

Park, N.

H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
[PubMed]

Park, N. K.

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Park, Q. H.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Park, Q.-H.

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Park, S. J.

S. J. Park, B. H. Son, S. J. Choi, H. S. Kim, and Y. H. Ahn, “Sensitive detection of yeast using terahertz slot antennas,” Opt. Express 22(25), 30467–30472 (2014).
[PubMed]

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

Park, W. K.

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

Park, Y. M.

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

Parrott, E. P. J.

E. P. J. Parrott, Y. Sun, and E. Pickwell-MacPherson, “Terahertz spectroscopy: Its future role in medical diagnoses,” J. Mol. Struct. 1006, 66–76 (2011).

Pickwell-MacPherson, E.

E. P. J. Parrott, Y. Sun, and E. Pickwell-MacPherson, “Terahertz spectroscopy: Its future role in medical diagnoses,” J. Mol. Struct. 1006, 66–76 (2011).

Planken, P. C. M.

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Plaxco, K. W.

J. Xu, K. W. Plaxco, and S. J. Allen, “Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy,” Protein Sci. 15(5), 1175–1181 (2006).
[PubMed]

Rao, G.

H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
[PubMed]

Sarukura, N.

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

Sasakawa, H.

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

Seo, M.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Seo, M. A.

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Shah, N. C.

P. L. Stiles, J. A. Dieringer, N. C. Shah, and R. P. Van Duyne, “Surface-Enhanced Raman spectroscopy,” Annu. Rev. Anal. Chem. (Palo Alto, Calif.) 1, 601–626 (2008).
[PubMed]

Sheiner, L. B.

L. B. Sheiner and S. L. Beal, “Evaluation of methods for estimating population pharmacokinetic parameters. II. Biexponential model and experimental pharmacokinetic data,” J. Pharmacokinet. Biopharm. 9(5), 635–651 (1981).
[PubMed]

Smith, D. S.

H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
[PubMed]

Smith, M. A.

A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
[PubMed]

Son, B. H.

Son, J.-H.

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Song, C.-S.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

Stiles, P. L.

P. L. Stiles, J. A. Dieringer, N. C. Shah, and R. P. Van Duyne, “Surface-Enhanced Raman spectroscopy,” Annu. Rev. Anal. Chem. (Palo Alto, Calif.) 1, 601–626 (2008).
[PubMed]

Sun, Y.

E. P. J. Parrott, Y. Sun, and E. Pickwell-MacPherson, “Terahertz spectroscopy: Its future role in medical diagnoses,” J. Mol. Struct. 1006, 66–76 (2011).

Suwal, O. K.

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Szmacinski, H.

H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
[PubMed]

Tamura, A.

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

Tominaga, K.

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

Uhd Jepsen, P.

B. M. Fischer, M. Walther, and P. Uhd Jepsen, “Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy,” Phys. Med. Biol. 47(21), 3807–3814 (2002).
[PubMed]

Van Duyne, R. P.

P. L. Stiles, J. A. Dieringer, N. C. Shah, and R. P. Van Duyne, “Surface-Enhanced Raman spectroscopy,” Annu. Rev. Anal. Chem. (Palo Alto, Calif.) 1, 601–626 (2008).
[PubMed]

Walker, G. C.

A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
[PubMed]

Walt, D. R.

B. G. Healey and D. R. Walt, “Improved fiber-optic chemical sensor for penicillin,” Anal. Chem. 67(24), 4471–4476 (1995).
[PubMed]

Walther, M.

B. M. Fischer, M. Walther, and P. Uhd Jepsen, “Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy,” Phys. Med. Biol. 47(21), 3807–3814 (2002).
[PubMed]

Wang, H.

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Wen, L.

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Witten, T. A.

T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
[PubMed]

Woo, D. H.

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

Xu, G.

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Xu, J.

J. Xu, K. W. Plaxco, and S. J. Allen, “Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy,” Protein Sci. 15(5), 1175–1181 (2006).
[PubMed]

Yamamoto, K.

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

Zell, M.

K. Ballschmiter and M. Zell, “Analysis of polychlorinated biphenyls (PCB) by glass capillary gas chromatography,” Fresenius J. Anal. Chem. 302, 20–31 (1980).

Zhang, Y.

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Zhao, Y.

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Zinovev, N. N.

A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
[PubMed]

Anal. Chem. (1)

B. G. Healey and D. R. Walt, “Improved fiber-optic chemical sensor for penicillin,” Anal. Chem. 67(24), 4471–4476 (1995).
[PubMed]

Annu. Rev. Anal. Chem. (Palo Alto, Calif.) (1)

P. L. Stiles, J. A. Dieringer, N. C. Shah, and R. P. Van Duyne, “Surface-Enhanced Raman spectroscopy,” Annu. Rev. Anal. Chem. (Palo Alto, Calif.) 1, 601–626 (2008).
[PubMed]

Appl. Phys. Lett. (1)

H. R. Park, Y. M. Park, H. S. Kim, J. S. Kyoung, M. A. Seo, D. J. Park, Y. H. Ahn, K. J. Ahn, and D. S. Kim, “Terahertz nanoresonators: Giant field enhancement and ultrabroadband performance,” Appl. Phys. Lett. 96, 121106 (2010).

Biophys. J. (1)

K. Yamamoto, K. Tominaga, H. Sasakawa, A. Tamura, H. Murakami, H. Ohtake, and N. Sarukura, “Terahertz Time-Domain Spectroscopy of Amino Acids and Polypeptides,” Biophys. J. 89(3), L22–L24 (2005).
[PubMed]

Biotechnol. Bioeng. (1)

H. Szmacinski, D. S. Smith, M. A. Hanson, Y. Kostov, J. R. Lakowicz, and G. Rao, “A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture,” Biotechnol. Bioeng. 100(3), 448–457 (2008).
[PubMed]

Fresenius J. Anal. Chem. (1)

K. Ballschmiter and M. Zell, “Analysis of polychlorinated biphenyls (PCB) by glass capillary gas chromatography,” Fresenius J. Anal. Chem. 302, 20–31 (1980).

IEEE Trans. Terahertz Sci. Technol. (1)

D.-K. Lee, G. Kim, C. Kim, Y. M. Jhon, J. H. Kim, T. Lee, J.-H. Son, and M. Seo, “Ultrasensitive Detection of Residual Pesticides Using THz Near-Field Enhancement,” IEEE Trans. Terahertz Sci. Technol. 6, 389 (2016).

J. Mol. Struct. (1)

E. P. J. Parrott, Y. Sun, and E. Pickwell-MacPherson, “Terahertz spectroscopy: Its future role in medical diagnoses,” J. Mol. Struct. 1006, 66–76 (2011).

J. Near Infrared Spectrosc. (1)

J. Pharmacokinet. Biopharm. (1)

L. B. Sheiner and S. L. Beal, “Evaluation of methods for estimating population pharmacokinetic parameters. II. Biexponential model and experimental pharmacokinetic data,” J. Pharmacokinet. Biopharm. 9(5), 635–651 (1981).
[PubMed]

J. Phys. Chem. A (1)

M. D. King, W. Ouellette, and T. M. Korter, “Noncovalent Interactions in Paired DNA Nucleobases Investigated by Terahertz Spectroscopy and Solid-State Density Functional Theory,” J. Phys. Chem. A 115(34), 9467–9478 (2011).
[PubMed]

J. Phys. Chem. B (1)

H. Hu and R. G. Larson, “Marangoni effect reverses coffee-ring depositions,” J. Phys. Chem. B 110(14), 7090–7094 (2006).
[PubMed]

Laser Photonics Rev. (1)

X. Hu, G. Xu, L. Wen, H. Wang, Y. Zhao, Y. Zhang, D. R. S. Cumming, and Q. Chen, “Metamaterial absorber integrated microfluidic terahertz sensors,” Laser Photonics Rev. 10, 962–969 (2016).

Nano Lett. (1)

H.-R. Park, K. J. Ahn, S. Han, Y.-M. Bahk, N. Park, and D.-S. Kim, “Colossal Absorption of Molecules Inside Single Terahertz Nanoantennas,” Nano Lett. 13(4), 1782–1786 (2013).
[PubMed]

Nat. Mater. (1)

T. P. Bigioni, X.-M. Lin, T. T. Nguyen, E. I. Corwin, T. A. Witten, and H. M. Jaeger, “Kinetically driven self assembly of highly ordered nanoparticle monolayers,” Nat. Mater. 5(4), 265–270 (2006).
[PubMed]

Nat. Photonics (1)

M. A. Seo, H. R. Park, S. M. Koo, D. J. Park, J. H. Kang, O. K. Suwal, S. S. Choi, P. C. M. Planken, G. S. Park, N. K. Park, Q. H. Park, and D. S. Kim, “Terahertz field enhancement by a metallic nano slit operating beyond the skin-depth limit,” Nat. Photonics 3, 152–156 (2009).

Opt. Express (1)

Phys. Med. Biol. (2)

B. M. Fischer, M. Walther, and P. Uhd Jepsen, “Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy,” Phys. Med. Biol. 47(21), 3807–3814 (2002).
[PubMed]

A. J. Fitzgerald, E. Berry, N. N. Zinovev, G. C. Walker, M. A. Smith, and J. M. Chamberlain, “An introduction to medical imaging with coherent terahertz frequency radiation,” Phys. Med. Biol. 47(7), R67–R84 (2002).
[PubMed]

Protein Sci. (1)

J. Xu, K. W. Plaxco, and S. J. Allen, “Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy,” Protein Sci. 15(5), 1175–1181 (2006).
[PubMed]

Sci. Rep. (3)

S. J. Park, J. T. Hong, S. J. Choi, H. S. Kim, W. K. Park, S. T. Han, J. Y. Park, S. Lee, D. S. Kim, and Y. H. Ahn, “Detection of microorganisms using terahertz metamaterials,” Sci. Rep. 4, 4988 (2014).
[PubMed]

D.-K. Lee, J.-H. Kang, J. Kwon, J.-S. Lee, S. Lee, D. H. Woo, J. H. Kim, C.-S. Song, Q. H. Park, and M. Seo, “Nano metamaterials for ultrasensitive Terahertz biosensing,” Sci. Rep. 7(1), 8146 (2017).
[PubMed]

D.-K. Lee, J.-H. Kang, J.-S. Lee, H.-S. Kim, C. Kim, J. H. Kim, T. Lee, J.-H. Son, Q.-H. Park, and M. Seo, “Highly sensitive and selective sugar detection by terahertz nano-antennas,” Sci. Rep. 5, 15459 (2015).
[PubMed]

Science (1)

F. F. Jöbsis, “Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters,” Science 198(4323), 1264–1267 (1977).
[PubMed]

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Figures (4)

Fig. 1
Fig. 1 (a) Schematic illustration of concept of sweeping AuNPs inside the nano slot area using a PDMS squeegee. (b) THz detection using nano-slot-antenna array sensing chip. (c) FDTD-calculated cross-sectional THz near-field maps around a nano antenna, producing highly enhanced local fields inside the slot. The bottom gray area represents the silicon substrate, and the nanoparticles were drawn over the simulation image for the conceptual purpose. (d) Concept of THz transmission signal analysis in terms of a transmission reduction (ΔT) and a frequency shift (Δλ) by insertion of nanoparticles (NPs) inside the nano antenna.
Fig. 2
Fig. 2 Schematic illustrations of the drop-casting (a; top line) and the sweeping (b; bottom line) techniques. Microscopic image of AuNPs spread over the nano slot array after five cycles of solvent drop and evaporation (c), and corresponding SEM images of a nano slot at w = 130 nm (e) and w = 500 nm (f). Microscopic image of AuNPs over the array after 5 sets of drop-casting procedure, followed by sweeping procedures (d) and corresponding SEM images of each sample at w = 130 nm (g) and w = 500 nm (h). Counted AuNP ratio in nano slot using two techniques (i).
Fig. 3
Fig. 3 (a) Schematic illustrations of a single cycle of sweeping methods, followed by THz detection of AuNPs. THz transmission spectra measured for AuNPs over the w = 130 nm (b, c), and w = 500 nm (d, e) slots by drop casting method only (b, d), and by additional sweeping method (c, e) in each cycle, respectively.
Fig. 4
Fig. 4 Quantitative analysis of ΔT (a, c) and Δf (b, d) as a function of AuNP concentration. The AuNPs over the w = 130 nm (a, b), and w = 500 nm (c, d) slots and their corresponding THz transmissions are also represented. After evaporation of last cycles of experiments in both methods, SEM images for drop-casted sample (e), and swept sample (f) in w = 500 nm slots were taken.

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