A method has been developed for the determination of silicone in breast tissue samples using a graphite furnace continuum source atomic absorption spectrometer. Silicone was measured as Si present in a heptane extract of the dried tissue samples. Thirty tissue samples were examined from 16 women having silicone gel-filled breast implants. Concentrations of Si in the dried tissue samples ranged from below the method detection limit of 3 ppm, to 6%.
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