Polarization Sensitive Optical Coherence Tomography-Guided Percutaneous Radiofrequency Ablation in Left Atrium of Living Swine

Xiaowei Zhao; Ohad Ziv; Ohad Ziv; Reza Mohammadpour; Benjamin Crosby; Walter J. Hoyt; Walter J. Hoyt; Michael W. Jenkins; Michael W. Jenkins; Christopher Snyder; Christopher Snyder; Kenneth R. Laurita; Kenneth R. Laurita; Andrew M. Rollins; Andrew M. Rollins

doi:10.1364/TRANSLATIONAL.2020.TW4B.3

Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN)
OSA Technical Digest (Optica Publishing Group, 2020),
paper TW4B.3
•https://doi.org/10.1364/TRANSLATIONAL.2020.TW4B.3

Polarization Sensitive Optical Coherence Tomography-Guided Percutaneous Radiofrequency Ablation in Left Atrium of Living Swine

Xiaowei Zhao, Ohad Ziv, Reza Mohammadpour, Benjamin Crosby, Walter J. Hoyt, Michael W. Jenkins, Christopher Snyder, Kenneth R. Laurita, and Andrew M. Rollins

Clinical and Translational Biophotonics 2020

Washington, DC United States
20–23 April 2020
ISBN: 978-1-943580-74-3

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Cardiovascular (TW4B)

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X. Zhao, O. Ziv, R. Mohammadpour, B. Crosby, W. J. Hoyt, M. W. Jenkins, C. Snyder, K. R. Laurita, and A. M. Rollins, "Polarization Sensitive Optical Coherence Tomography-Guided Percutaneous Radiofrequency Ablation in Left Atrium of Living Swine," in Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN), OSA Technical Digest (Optica Publishing Group, 2020), paper TW4B.3.

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Abstract

Atrial fibrillation (AF) is the most common sustained arrhythmia in the western world. Pulmonary vein isolation (PVI) using radiofrequency ablation (RFA) is frequently conducted to treat AF. However, current PVI procedures for lesion formation are guided only with indirect information, which may lead to non-transmural lesions, and contribute to the high recurrence of AF. Therefore, direct lesion quality feedback may potentially improve PVI efficacy. To study the real-time direct guidance capability of polarization sensitive optical coherence tomography (PSOCT), a custom-designed integrated PSOCT-RFA catheter was prototyped and tested in RFA procedures in the left atria of living swine.

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