Influence of oxy-, deoxy- and met-hemoglobin absorption in interstitial photodynamic therapy

C. Heckl; M. Aumiller; A. Rühm; H Stepp; R. Sroka

doi:10.1364/TRANSLATIONAL.2020.TW1B.8

Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN)
OSA Technical Digest (Optica Publishing Group, 2020),
paper TW1B.8
•https://doi.org/10.1364/TRANSLATIONAL.2020.TW1B.8

Influence of oxy-, deoxy- and met-hemoglobin absorption in interstitial photodynamic therapy

C. Heckl, M. Aumiller, A. Rühm, H Stepp, and R. Sroka

Clinical and Translational Biophotonics 2020

Washington, DC United States
20–23 April 2020
ISBN: 978-1-943580-74-3

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C. Heckl, M. Aumiller, A. Rühm, H. Stepp, and R. Sroka, "Influence of oxy-, deoxy- and met-hemoglobin absorption in interstitial photodynamic therapy," in Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN), OSA Technical Digest (Optica Publishing Group, 2020), paper TW1B.8.

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Abstract

During illumination in interstitial photodynamic therapy, transmitted treatment light monitoring showed a reduction in intensity. It can be shown experimentally that light-induced hemoglobin de-oxygenation and methemoglobin formation leads to an increase in light absorption.

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