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Conferences > NTM > 2019 > JW4C > JW4C.8
  • Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)
  • OSA Technical Digest (Optica Publishing Group, 2019),
  • paper JW4C.8
  • •https://doi.org/10.1364/BODA.2019.JW4C.8

Automatic Correction of Pixel-dependent Noise: Towards the Ideal sCMOS Camera

Biagio Mandracchia, Xuanwen Hua, Changliang Guo, and Shu Jia

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Abstract

sCMOS cameras are very appealing for fluorescence microscopy but they suffer from high readout noise. We propose a non-iterative, fast, and unsupervised algorithm that erases sCMOS noise without losing the quantitative information of fluorescence signal.

© 2019 The Author(s)

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