The design of protocols for an effective in-vivo therapeutic outcome relies on the knowledge of the nanoparticle localization and concentration. In order to create a methodology based on optical absorption maps gold nanoparticles were embedded in tissue simulating media. Silicone-based phantoms were used to mimic the scattering and absorption properties of tissues and determine the accuracy of spatial frequency domain imaging to localize and quantify the nanoparticles with a 3D perspective.

© 2018 The Author(s)

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