Single Molecule Studies of Unstructured Protein Function and Dynamics

Abhinav Nath; Corey O’Hern; Corey O’Hern; Andrew D. Miranker; Elizabeth Rhoades; Elizabeth Rhoades

doi:10.1364/FIO.2011.FTuH1

Frontiers in Optics 2011/Laser Science XXVII
OSA Technical Digest (Optica Publishing Group, 2011),
paper FTuH1
•https://doi.org/10.1364/FIO.2011.FTuH1

Single Molecule Studies of Unstructured Protein Function and Dynamics

Abhinav Nath, Corey O’Hern, Andrew D. Miranker, and Elizabeth Rhoades

Frontiers in Optics 2011

San Jose, California United States
16–20 October 2011
ISBN: 978-1-55752-917-6

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Single Molecule Detection, Diagnostics and Therapy I (FTuH)

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A. Nath, C. O’Hern, A. D. Miranker, and E. Rhoades, "Single Molecule Studies of Unstructured Protein Function and Dynamics," in Frontiers in Optics 2011/Laser Science XXVII, OSA Technical Digest (Optica Publishing Group, 2011), paper FTuH1.

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Abstract

Unstructured proteins are biologically important, but challenging to characterize by traditional biophysical methods. We describe how single-molecule fluorescence can probe the conformations of disease-related unstructured proteins, in solution or bound to relevant partners.

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