Since the light is essentially non-contact and non-destructive, single laser beam optical trapping1 is expected to be a new method for physically manipulating single biological cells in experimental cell biology and relevant fields. Up to now, however, only a TEM00 fundamental mode laser beam (Gaussian beam) has been used for the optical trapping of biological cells because strong focusing the laser beam is required.1,2

© 1991 Optical Society of America

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